Plasma Atrial Natriuretic Peptide Level As an Index for the Severity of Congestive Heart Failure
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چکیده
منابع مشابه
Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations.
Atrial natriuretic peptide (ANP) and B-type natriuretic peptide decrease blood pressure and cardiac hypertrophy by activating natriuretic peptide receptor A (NPR-A), a transmembrane guanylyl cyclase also known as guanylyl cyclase A. Inactivation of NPR-A is a potential mechanism for the renal hyporesponsiveness observed in congestive heart failure (CHF) but direct data supporting this hypothesi...
متن کاملThe effect of treatment of congestive heart failure on plasma atrial natriuretic peptide concentration: a longitudinal study.
Eleven patients with acute congestive heart failure were studied during treatment with a loop diuretic. Plasma concentrations of atrial natriuretic peptide were considerably increased before treatment and with successful treatment returned progressively towards normal values. There was a statistically significant correlation between plasma atrial natriuretic peptide concentration and both jugul...
متن کاملDifferent secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure.
BACKGROUND The plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are increased in relation to the severity of congestive heart failure (CHF). This study was designed to examine whether the secretion patterns of ANP and BNP vary with underlying cardiac disorders of CHF with different degrees of overload in atria and ventricles. METHODS AND RESULTS We measure...
متن کاملConcentrations of brain natriuretic peptide in treated congestive heart failure.
CLINICALCHEMISTRY, Vol.37, No. 5, 1991 765 (sandwich) assays. II. Studies on the nature of the “high-dose hook-effect.” Immunochemistry 1978;15:77-82. 9. Miles LEM, Lipschitz DA, Bieber CP, et al. Measurement of serum ferritin by a 2-site immunoradiometric assay. Anal Biochem 1974;61:209-24. 10. Green B., Watson LB., Saab GA, et al. “Normal” serum ferritin-a caution. Blood 1977;50:545-7. 11. Ry...
متن کاملBrain natriuretic peptide, clinical reasoning, and congestive heart failure.
Dyspnea is a sensation of the need to breathe or difficult or labored breathing. It leads to 2.5 million visits to healthcare providers annually in the United States. A number of abnormalities can cause dyspnea, and determining the etiology will allow institution of timely therapy and avoidance of unnecessary diagnostic tests. Brain natriuretic peptide (BNP) is a neurohormone secreted by the le...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 1987
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960100806